You might say that Dr. Begum Mathyk is following the interstellar path once blazed by Star Trek -- with just one minor twist. True to the spirit of the Starship Enterprise鈥檚 adventurous motto, Dr. Mathyk鈥檚 mission is to boldly go where no OB-GYN has gone before.
To be clear, the USF Health Morsani College of Medicine physician and assistant professor in the Department of Obstetrics and Gynecology isn鈥檛 angling for a shuttle ride into space, the final frontier. But she has taken a lead role on Planet Earth in analyzing the effects of space travel on women鈥檚 health. It is a place that has captivated her imagination since she was a child growing up in Istanbul, and now is the focus of Dr. Mathyk鈥檚 wide-ranging studies.
鈥淢y interest is space biology and doing my best to advocate for women鈥檚 health on Earth and beyond,鈥� she said.
Dr. Mathyk has been doing precisely that through a multitude of endeavors and publications worthy of any Star Trek captain鈥檚 log. Just consider:
鈥� She is an active member of NASA鈥檚 GeneLab group, consisting of researchers in the field of space biology. They have published a space biology research package using data gathered from Inspiration 4, the world鈥檚 first all-civilian, four-person mission to orbit 鈥� including two men and two women.
鈥� Dr. Mathyk served as first author on two papers published June 11 as part of this special . The first is in the Nature Communications Biology journal entitled, 鈥�.鈥� The second, in npj Women鈥檚 Health, is entitled 鈥�.鈥�&苍产蝉辫;
鈥� She is also a member of the NASA STAR course fellow program, receiving biosciences training, and in 2023 presented at the annual international space research conference held by the American Society for Gravitational and Space Research. As part of that, an illustration Dr. Mathyk conceived of and commissioned鈥� depicting a female astronaut and an impressionistic uterus 鈥� won first prize in the conference鈥檚 art competition.
鈥� Also this year, she presented on female reproductive health in space at NASA鈥檚 annual
GeneLab symposium.
鈥淚 feel like sometimes people are embarrassed to talk about women鈥檚 health and certain things, but it鈥檚 our nature, and it鈥檚 been with us since the caveman days,鈥� she said.
Dr. Mathyk is among the very few physicians addressing the topic in an intensive way.
鈥淚 just say that this is my job on Earth and I鈥檓 not going to change that,鈥� she said. 鈥淭here are space biology PhD researchers working in this field, but I am the only female OB-GYN in the United States actively doing space research.鈥�
There are certain specific areas Dr. Mathyk has targeted to gain a greater understanding of space travel on women, such as menopause, menstrual irregularities, and the possible effects on fertility or infertility, as well as gynecological surgery and imaging.
鈥淚 don鈥檛 want to focus on just one thing 鈥� when you say women鈥檚 health, it鈥檚 very broad,鈥� she explained. 鈥淚鈥檓 looking at whether women may have an increased risk for cancer, if they are they going to have irregular bleeding or could experience fertility problems. People also talk about pregnancy in space, but before that, we need to understand how we鈥檙e going to maintain our health in a non-pregnant state. These are the areas I鈥檓 exploring.鈥�
While Dr. Mathyk鈥檚 chief concern is ensuring the health of women space travelers, she also is motivated by a desire to keep future female crew members healthy and functioning effectively on a given mission.
鈥淵ou want your team member when in an extreme, remote setting to be feeling good and working together with the team,鈥� she said. 鈥淚t鈥檚 all about health of the individual and health of the team.鈥�
She also feels a pressing need to learn more due to the increase in space travel, not just NASA-funded flights but private enterprise, and the likelihood that more everyday citizens will be paying their way into space in the coming years.
鈥淲hat if I have a patient 10 years from now, and they ask me, 鈥業s it safe to fly into space?鈥� 鈥� she said. 鈥淪o from a physician鈥檚 perspective, I started looking at what I should know and how I am going to counsel those women. That was really how my interest in this developed.鈥�
It also has roots in Dr. Mathyk鈥檚 days as a little girl in Turkey, where her mother worked as an anesthesiologist and father served in the military. She grew up with her mom, learning how she had finished first in her class in college and watching her work extremely hard at her job. She also became an avid fan of the 1980s cartoon Thundercats, with its cat-like humanoid characters from a distant planet, and He-Man and the Masters of the Universe.
鈥淚 was always interested in space and always a curious kid, up to the point of getting myself in trouble,鈥� she recalled. 鈥淚 was always wondering, 鈥榃hy does something happen?鈥� and I鈥檇 do little experiments at home that didn鈥檛 always work out. I always liked science 鈥� my husband says I have a brain wired for imagination and science. And I think I developed that out-of-the-box thinking as a kid.鈥�
In middle and high school, she developed another interest 鈥� swimming. Dr. Mathyk eventually became good enough to make Turkey鈥檚 national team in the 200 fly, competing in the European Championships and winning her share of medals along the way. She also matched her mother鈥檚 academic heights, eventually finishing as class valedictorian at Yeditepe University School of Medicine in Istanbul.
She could easily have had a successful OB-GYN career in Turkey after graduating in 2007. But her curious and adventurous spirit instilled a desire to expand her horizons. Her husband, Scott, then an English-language elementary school teacher from Canada, urged her to take the step.
鈥淗e said, 鈥榊ou have great potential and you may one day benefit humankind, so I will support you,鈥� 鈥� she said.
So off Mathyk boldly went: first to Boston for a post-doctoral fellowship at Harvard-MIT Health Sciences and Technologies; next as a visiting scholar in reproductive endocrinology and infertility at the University of North Carolina 鈥� Chapel Hill; then back to Boston for her OB-GYN residency at Tufts University. Later, she completed an Aerospace Medicine Clerkship at NASA鈥檚 Johnson Space Center in Houston.
Three years ago, Dr. Mathyk landed a position at HCA Florida Brandon Hospital. But last year, she heard USF Health鈥檚 OB-GYN department was looking to hire new faculty members. Her husband had already found work at Moffitt Cancer Center, and the couple wanted to remain in the area, so she applied and was thrilled to be hired. She has loved the support she has received in applying for funding and was excited to make a presentation to Charles J. Lockwood, MD, MHCM, executive vice president of USF Health and dean of the Morsani College of Medicine, about her space research.
Now, she is excited to begin a new chapter in her life with the reproductive endocrinology and infertility fellowship at USF, while continuing her work into women鈥檚 health in space research.
She has even picked up a nickname along the way. During her NASA Aerospace Medicine Clerkship in 2022, Top Gun: Maverick was in theaters. And just like the movie, everyone she worked with seemed to have their own nickname. She asked her colleagues what they thought her name should be, and in a nod to the Anthony Edwards鈥� Top Gun character Goose, they had the answer.
鈥淭hey told me I would be Stork,鈥� she said with a laugh.
A perfect moniker for the OB-GYN focused starward on women鈥檚 health.